Agent Name

cis-1,2-Dichloroethylene

Alternative Name

cis-Acetylene dichloride

CAS Number

156-59-2

Formula

C2-H2-Cl2

Major Category

Solvents

Synonyms

(Z)-1,2-Dichloroethene; (Z)-1,2-Dichloroethylene; Acetylene dichloride, cis-; Ethene, 1,2-dichloro-, (Z)-; Ethylene, 1,2-dichloro-, (Z)-; HCC 1130c; R 1130c; cis-1,2-Dichloroethene; cis-Dichloroethylene; Ethene, 1,2-dichloro-, (1Z)-; [ChemIDplus] UN1150

Category

Chlorinated Aliphatics

Description

Colorless liquid with an odor like ether; [CAMEO] Pleasant odor; [Acros Organics MSDS]

Sources/Uses

Used as a solvent (fats, phenol, camphor, etc.) and as an intermediate; [Merck Index] Also used to make rubber, as a refrigerant, an additive to dye and lacquer solutions, to retard fermentation, and in medicines, perfumes, and thermoplastics; [NTP]

Comments

Causes general anesthesia, convulsions, and fatty liver degeneration in inhalation lethal-concentration studies of rodents; [RTECS] Irritating and narcotic at high vapor concentrations; May cause irritation and CNS depression; Liver and kidney injury observed in experimental animals; [NTP] May polymerize; A moderate skin and eye irritant; Inhalation of high concentrations may have narcotic effects; [Acros Organics MSDS] See "1,2-Dichloroethylene, all isomers."

Reference Link

ATSDR - ToxFAQs: 1,2-Dichloroethene

Exposure Assessment
TLV (ACGIH)

200 ppm

PEL (OSHA)

200 ppm

MAK

200 ppm

IDLH (NIOSH)

1000 ppm

Vapor Pressure

200 mm Hg

Odor Threshold Low

0.08 ppm

Lethal Concentration

LC50 (rat) = 13,700 ppm

Explanatory Notes

Odor threshold from NTP;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: