Agent Name

Coenzyme A

CAS Number

85-61-0

Formula

C21-H36-N7-O16-P3-S

Major Category

Biological Agents

Synonyms

Depot-Zeel; Zeel; [ChemIDplus] CoA; Adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate) P'-[(R-)3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl]ester; [Merck Index] Coenzyme A (free acid); [Avanti Polar Lipids MSDS]

Category

Other Biomolecules

Description

White solid; [Merck Index] White powder; [Avanti Polar Lipids MSDS]

Sources/Uses

Essential cofactor in acetyl transfer reactions found in mammalian cells and many microorganisms; [Merck Index] "Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle." [Wikipedia]

Comments

Rapidly oxidizes in air forming the catalytically inactive disulfide; [Merck Index] May cause irritation; [Avanti Polar Lipids MSDS]

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