Agent Name

Collagenase

CAS Number

9001-12-1

Formula

Unspecified

Major Category

Biological Agents

Synonyms

Biozyme C salbe; Clostridial collagenase; Clostridiopeptidase A; Clostridium histolyticum collagenase; Collagen protease; Collagenase A; Euphaulysin; Liberase; MMP-1; MMP-8 ; Matrix metalloproteinase-1; Matrix metalloproteinase-8; Morikraz; Santyl; Santyl salbe; Soycollagestin; Ulcerase salbe; Xiaflex; [ChemIDplus] Iruxol; [Merck Index]

Category

Enzymes

Description

Powder; [Sigma-Aldrich MSDS]

Sources/Uses

An enzyme that can digest native collagen; Used in collagen research, in tissue culture studies, and as a debriding agent; [Merck Index]

Comments

Causes effects on joints and effects on inflammation in 4-day intermittent parenteral studies of rabbits; [RTECS] A skin and strong eye irritant; May cause respiratory sensitization; [Sigma-Aldrich MSDS] See "ENZYMES."

Adverse Effects
Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: