Agent Name

Concanavalin A

CAS Number

11028-71-0

Major Category

Other Uses

Synonyms

CON A; Concanavaline A; Ricin-toxin con A; [ChemIDplus] ConA; [Merck Index]

Category

Biochemical Research

Description

Lyophilized powder; [Sigma-Aldrich MSDS]

Sources/Uses

A plant protein in the lectin family; Isolated from jack beans; Used as a biochemical reagent and as a probe in cell biology (membrane dynamics and cell division); [Merck Index]

Comments

Teratogenic effects observed in rabbits (intraperitoneal) and mice (intravenous) exposed during gestation; [ToxPlanet: Shepard's Catalog of Teratogenic Agents] Causes diffuse hepatitis and changes in thymus and spleen weights in acute intravenous studies of mice; Causes decreased cellular immune response in 30-day intermittent intraperitoneal studies of mice; [RTECS] May cause irritation; May cause skin and respiratory sensitization; May cause toxicity to human reproduction; [Sigma-Aldrich MSDS] PubMed: no results for 11028-71-0 AND (allergic OR sensitizer OR sensitization OR asthma)[Title];

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.