Agent Name

Iodochlorhydroxyquin

Alternative Name

Clioquinol

CAS Number

130-26-7

Formula

C9-H5-Cl-I-N-O

Major Category

Other Uses

Synonyms

Clioquinol; 5-Chloro-7-iodo-8-hydroxyquinoline; 5-Chloro-7-iodo-8-quinolinol; 5-Chloro-8-hydroxy-7-iodoquinoline; Chloroiodoquin; Chlorojodochin; Cifoform; Dioquinol; Quin-O-Creme; 7-Iodo-5-chloroxine; Lekosept; Domeform; Clioquinol; Amebil; Alchloquin; Amoenol; Bactol; Barquinol; Budoform; Chinoform; Eczecidin; Enteroquinol; Entero-Septol; Entero-Vioform; Enterozol; Entrokin; Hi-Enterol; Iodochlorhydroxyquin; Iodochloroxyquinoline; Iodoenterol; Nioform; Quinambicide; Rometin; Quinoform; Vioform; Iodochlorohydroxyquinol; Iodochlorohydroxyquinoline; Chloroiodoquine; 7-Iodo-5-chloro-8-hydroxyquinoline; Cliquinol; Emaform; Entero-bio form; Enterum locorten; Hydriodide-enterol; Iodenterol; Vioform n.n.r.; [ChemFinder]

Category

Pharmaceuticals

Sources/Uses

Used as a medicinal cream, ointment, or powder; [HSDB]

Comments

Allergic contact dermatitis reported in patients using this antibiotic topically; [Marks, p. 123-4] An epidemic of subacute myelo-optico-neuropathy occurred in Japan from 1956 until 1970. Approximately 10,000 cases were reported with visual impairment, lower extremity paresthesias and weakness, and other symptoms. Symptoms resolved after the oral medication was discontinued. Neurotoxicity developed in patients who received total doses greater that 750 mg/day for four weeks. [HSDB]

Adverse Effects
Skin Sensitizer

Yes

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: