Agent Name

Chlorpromazine

CAS Number

50-53-3

Formula

C17-H19-Cl-N2-S

Major Category

Other Uses

Synonyms

2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine; Chloropromazine; Ormazine; Thor-prom; Thorazine; Largactil; [ChemFinder]

Category

Pharmaceuticals

Comments

Allergic and photoallergic contact dermatitis reported in pharmaceutical, healthcare, and animal care workers; [Kanerva, p. 1138] As an oral medication, chlorpromazine is used to treat schizophrenia. Many side effects have been reported after ingestion of therapeutic doses, including drug-induced hepatitis. [HSDB] Chlorpromazine may induce photosensitivity in patients taking chlorpromazine systemically (photodrug reaction). [Marks, p. 201-3] Danger of photo-contact dermatitis; [MAK]

Exposure Assessment
Explanatory Notes

"Danger of sensitization of skin." [MAK]

Adverse Effects
Skin Sensitizer

Yes

Dermatotoxin

Contact Dermatitis, Photoallergic

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: