Agent Name

Diisocyanatomethylbenzene

CAS Number

1321-38-6

Formula

C9-H6-N2-O2

Major Category

Plastics & Rubber

Synonyms

Isocyanic acid, methylphenylene ester; Benzene, diisocyanatomethyl-; [ChemIDplus] Crudell TDI; 2,4-TDI unspecified isomer; [INCHEM PIMs] UN2078

Category

Diisocyanates

Description

Melting point = 20 deg C; [ChemIDplus] Colorless to yellow liquid or solid with a sweet, pungent, fruity odor; mp = 19.5-21.5 deg C; [INCHEM PIMs]

Sources/Uses

This is the crude form of toluene 2,4-diisocyanate (2,4-TDI) with an unspecified isomer ratio commercially available but not usually used; [INCHEM PIMs] Used to make polyurethane foams and coatings, elastomeric coating systems, adhesives, and sealants; Occupational exposure occurs in adhesives production, insulation application, resin and lacquer production, chemical synthesis, paint spraying, polyurethane foam production, work with rubber, shipbuilding, textile processing, and wire coating; [INCHEM PIMs]

Comments

Reacts with water; Inhalation is the most dangerous route of exposure; May cause skin sensitization; Reports of eye irritation, corneal edema, and conjunctivitis; Inhalation may cause systemic effects and hypersensitivity reactions; Animal studies have demonstrated that dermal exposure can cause pulmonary sensitization; Inhalation of concentrations above 3.5 mg/m3 may cause chemical pneumonitis; [INCHEM PIMs] See "Toluene 2,4-diisocyanate."

Exposure Assessment
Vapor Pressure

0.01 mm Hg

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Toxic Pneumonitis

Yes

Fibrogenic

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: