Agent Name

Dimethyl malonate

CAS Number

108-59-8

Formula

C5-H8-O4

Major Category

Other Classes

Synonyms

Dimethyl 1,3-propanedioate; Dimethyl malonate; Dimethyl propanedioate; Malonic acid, dimethyl ester; Propanedioic acid, 1,3-dimethyl ester; Propanedioic acid, dimethyl ester; [ChemIDplus] DMM; Dimethylmalonate; [Reference #1]

Category

Esters, Other

Description

Liquid; [Merck Index] Colorless liquid with an ester-like odor; [Reference #1]

Sources/Uses

Naturally occurring as a volatile in fruits such as pineapples, bananas, and blackberries; Used as an intermediate for agrochemicals, pharmaceuticals, industrial chemicals, and other compounds; [Reference #1]

Comments

Causes no skin irritation and mild to moderate eye irritation in rabbits; No adverse effects observed in oral or dermal lethal-dose studies of rats (LD50s > 2,000 mg/kg); Reversible hepatocellular hypertrophy (considered indicative of liver metabolism rather than systemic toxicity) observed in an oral repeated-dose study of rats at the highest tested dose (1,000 mg/kg/day); No evidence of reproductive toxicity, developmental toxicity, or mutagenicity; [Reference #1] May cause irritation; [Alfa Aesar MSDS]

Reference Link

OECD SIDS: Malonic Acid Diesters - 2005

Exposure Assessment
Vapor Pressure

14.7 mm Hg

Explanatory Notes

VP = 0.37 mm Hg at 20 deg C; [Reference #1]

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.