Agent Name

Di-n-propylphthalate

CAS Number

131-16-8

Formula

C14-H18-O4

Major Category

Plastics & Rubber

Synonyms

1,2-Benzenedicarboxylic acid, dipropyl ester; Di-n-propyl phthalate; Dipropyl phthalate; n-Dipropyl phthalate; 1,2-Benzenedicarboxylic acid, 1,2-dipropyl ester; Phthalic acid, dipropyl ester; [ChemIDplus] Dipropyl benzene-1,2-dicarboxylate; Dipropyl ester phthalic acid; Phthalic acid dipropyl ester; [CAMEO]

Category

Phthalate Esters

Description

Colorless liquid; [CAMEO] Clear light yellow liquid; [Sigma-Aldrich MSDS]

Sources/Uses

Used to make plasticizers and plastics and for laboratory applications; [NTP]

Comments

Causes ptosis and somnolence in intraperitoneal lethal-dose studies of mice and rats (LDLo = 1,251 mg/kg); [RTECS] Reproductive toxicity in both sexes (shown by crossover mating) observed in oral study of mice at doses producing reduced parental weight gain; The high dose group (5% of feed equivalent to approximately 8,630 mg/kg) was sterile, had increased liver and kidney weights (without corresponding histopathology), and reduced seminal vesicles, epididymis, prostate, and testis weights, reduced sperm counts and motility, and increased sperm abnormalities; [NTP] May cause irritation; May cause reproductive toxicity; [Sigma-Aldrich MSDS] See "PHTHALATE ESTERS."

Exposure Assessment
Vapor Pressure

0.000132 mm Hg

Adverse Effects
Reproductive Toxin

Yes

Links to Other NLM Databases
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