Agent Name

Fenvalerate

CAS Number

51630-58-1

Formula

C25-H22-Cl-N-O3

Major Category

Pesticides

Synonyms

(+)-alpha-Cyano-3-phenoxybenzyl-(+)-alpha-(4-chlorophenyl)isovalerate; (Cyano(3-phenoxyphenyl)methyl-4-chloro-alpha-(1-methylethyl)phenylacetate); (RS)-alpha-Cyano-3-phenoxybenzyl (RS)-2-(4-chloro-phenyl)-3-methylbutyrate; (RS)-alpha-Cyano-3-phenoxybenzyl (RS)-2-(4-chlorophenyl)-3-methylbutyrate; 4-Chloro-alpha-(1-methylethyl)benzeneacetic acid cyano(3-phenoxyphenyl)methyl ester; Agrofen; Aqmatrine; Belmark; Cyano(3-phenoxyphenyl)methyl 4-chloro-alpha-(1-methylethyl)benzeneacetate; EPA Shaughnessy Code: 109301; Ectrin; Evercide 2362; Fenaxin; Fenkem; Fenkill; Fenoxin; Fenval; Fenvalerate; Furitrothion; Gold crest tribute; Insectral; OMS-2000; Phenoxin; Phenvalerate; Pydrin; S 5602; S-5602; SD 43775; Sanmarton; Sumibac; Sumicidin; Sumicidin 20E; Sumifleece; Sumifly; Sumipower; Sumitick; Sumkidin; Tirade; Tribute; WL 43775; alpha-Cyano-3-phenoxybenzyl 2-(4-chlorophenyl)isovalerate; alpha-Cyano-3-phenoxybenzyl alpha-(4-chlorophenyl)isovalerate; alpha-Cyano-3-phenoxybenzyl alpha-isopropyl-4-chlorophenylacetate; alpha-Cyano-3-phenoxybenzyl-2-(4-chlorophenyl)-3-methylbutyrate; Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)-, cyano(3-phenoxyphenyl)methyl ester; Cyano(3-phenoxybenzyl)methyl 2-(4-chlorophenyl)-3-methylbutyrate; alpha-Cyano-(3-phenoxyphenyl)methyl-4-chloro-alpha-(1-methylethyl)benzeneacetate; [ChemIDplus] UN3352

Category

Pyrethrins/Pyrethroids

Description

Yellow liquid; [HSDB] Yellow or brown viscous liquid; [ICSC] Formulated as emulsifiable concentrates, ultra-low volume concentrates, dust powders, and wettable powders; [INCHEM HSG]

Sources/Uses

Used as an insecticide and medication; [HSDB]

Comments

Allergic contact dermatitis reported in farmers; [Kanerva, p. 1796] Pyrethroids have low toxicity to humans after dermal exposure. Of 573 dermal or ingestion poisoning cases in China, 51 patients had disturbed consciousness and 34 had seizures. Of those, only five were occupationally exposed. Seizures are more commonly related to exposures to fenvalerate, flucythrinate, cypermethrin, deltapermethrin, and fluvalinate. Seizures have not been reported after exposure to permethrin. Pyrethroids may also cause paresthesias after skin contact. Paresthesias (stinging and numbness) usually begin 1-2 hours after contact and resolve within 24 hours. [EPA Pesticides, p. 87-8] Pyrethrins cause liver injury when fed to animals at high doses. [EXTOXNET] A skin, eye, and respiratory tract irritant; May cause skin sensitization; May have effects on the nervous system; [ICSC] Occupational exposure may cause skin sensations and paresthesia; [INCHEM HSG] A skin and strong eye irritant; Toxic by ingestion; [Aldrich MSDS]

Restricted

US registration voluntarily cancelled by registrants in 2008; [EPA]

Reference Link

Contact sensitization by pesticides in farmers

Exposure Assessment
Vapor Pressure

1.5E-9 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Pyrethroid pesticide, liquid, toxic."

Reference Link

Sensitization risk of pyrethroid insecticides

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: