Agent Name

Dansyl chloride

CAS Number

605-65-2

Formula

C12-H12-Cl-N-O2-S

Major Category

Other Classes

Synonyms

1-Chlorosulfonyl-5-dimethylaminonaphthalene; 1-Dimethylaminonaphthalene-5-sulfonyl chloride; 5-Dimethylaminonaphthalene-1-sulfonyl chloride; DNS chloride; Dansyl; Dimethylaminonaphthalenesulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-; 5-Dimethylaminonaphthalene-1-sulphonyl chloride; [ChemIDplus] 5-(Dimethylamino)-1-naphthalenesulfonyl chloride; [Merck Index] 1-(Dimethylamino)-5-naphthalenesulfonyl chloride; [RTECS] UN3261

Category

Naphthalenes

Description

Yellow-orange solid; [Merck Index] Orange powder; [Alfa Aesar MSDS]

Sources/Uses

Used in fluorescent labeling and high performance liquid chromatography (HPLC); [Merck Index] "Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis." [Wikipedia]

Comments

Intravenous LD50 (mouse) = 56 mg/kg; [RTECS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS]

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Corrosive solid, organic, n.o.s."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.