Agent Name

N,N-Dimethylethylamine

CAS Number

598-56-1

Formula

C4-H11-N

Major Category

Nitrogen Compounds

Synonyms

Dimethylethylamine; Ethanamine, N,N-dimethyl-; Ethylamine, N,N-dimethyl-; Methanamine, N-ethyl-N-methyl-; N-Ethyldimethylamine; Ethanamine, N,N-dimethyl-; Ethyldimethylamine; [ChemIDplus] N,N-Dimethyl ethyl amine; [Guide to Occupational Exposure Values, 2002] DMEA; Ethyldimethylamin; N,N-Dimethylethylamin; N,N-Dimethyl-ethylamine; [IUCLID] UN2733

Category

Amines, Aliphatic

Description

Clear colorless liquid with a strong odor of ammonia or fish; [CAMEO]

Sources/Uses

Used as a curing agent for cold-box sand molding in foundries, in the polymerization of polyamides, as intermediate for quaternary ammonium compounds, and as stabilizer for chlorinated hydrocarbons and vinyl derivatives; [HSDB] Used to make other chemicals; [CAMEO]

Comments

In an industrial hygiene survey of foundry workers, some high concentrations of dimethylethylamine were found associated with cold-box sand molding. [Appl Occup Environ Hyg 2001 Jan;16(1):66-77] Volunteers exposed to 40-50 mg/m3 for 8 hours experienced mucous membrane irritation and mild corneal edema. [Br J Ind Med 1991 Jan;48(1):26-9] Corrosive to skin; [Quick CPC] Occupational exposure to vapor reportedly causes eye irritation, visual disturbances (haze, blurred vision, lachrymation, and halo perception), and mild edema of corneal epithelium; Systemic effects reported (following suspected large releases) in foundry employees include dizziness, tightness and pain in the chest, abdominal cramps, increased heart rate, headache, and nausea; Emergency treatment: "Irritants"; [HSDB] Not sensitizing in guinea pig maximization test; Classified in the EU as: Causes burns; Harmful by inhalation and ingestion; Extremely flammable; [IUCLID] Causes burns; Harmful if swallowed or inhaled--can cause chemical pneumonitis; [Alfa Aesar MSDS]

Reference Link

Exposure to chemical agents in Swedish aluminum foundries and aluminum remelting plants--a comprehensive survey

Exposure Assessment
MAK

2 ppm

Vapor Pressure

352 mm Hg

Lethal Concentration

LC50 (rat) = 2,300-15,400 mg/m3/1hr

Explanatory Notes

Flash point = 10 deg F; The Guide in the Emergency Response Guidebook is for "Amines, flammable, corrosive, n.o.s."

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: