Agent Name

1,2-Dimethylhydrazine

CAS Number

540-73-8

Formula

C2-H8-N2

Major Category

Nitrogen Compounds

Synonyms

1,2-DMH; 1,2-Dimethyl-hydrazine; 1,2-Dimethylhydrazin [German]; DMH; Hydrazine, 1,2-dimethyl-; Hydrazomethane; N,N'-Dimethylhydrazine; SDMH; Symetryczna dwumetylohydrazyna; Symetryczna dwumetylohydrazyna [Polish]; Symmetrical-dimethylhydrazine; sym-Dimethylhydrazine; Dimethylhydrazine, symmetrical; [ChemIDplus] UN2382

Category

Hydrazines

Description

Colorless liquid with a fishy or ammonia-like odor; [NIOSH] Hygroscopic liquid; Fumes and gradually turns yellow in air; [Merck Index]

Sources/Uses

Used in research and not used commercially; [HSDB] Used in the production of photographic chemicals; [CAMEO]

Comments

Liquid causes second or third degree burns after short contact; [CHRIS] Patients poisoned by hydrazines may develop methemoglobinemia and liver injury; Emergency treatment: "Hydrazines"; [HSDB] Inhalation of hydrazine compounds in high concentrations can induce seizures and coma; Corrosive to skin; [Merck Index] Toxic after absorption through skin; Inhalation of high concentrations can induce pulmonary irritation and edema; [CAMEO] A strong reducing agent; An eye and respiratory tract irritant; May injure liver; Can be absorbed through skin; The kidney is target organ in experimental animals; [ICSC] Danger of skin sensitization; [MAK] Causes convulsions and dyspnea in lethal-dose inhalation studies of rats; [RTECS]

Exposure Assessment
TIH

Yes

Vapor Pressure

68 mm Hg

Lethal Concentration

LC50 (rat) = 280 ppm/4hr

Explanatory Notes

Highly flammable; Flash point = 5 deg F; [CAMEO]

Reference Link

ATSDR - ToxFAQs - Hydrazines

Adverse Effects
Skin Sensitizer

Yes

Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Probable Carcinogen

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: