Agent Name

N-Vinyl-2-pyrrolidone

Alternative Name

N-Vinyl-2-pyrrolidinone

CAS Number

88-12-0

Formula

C6-H9-N-O

Major Category

Plastics & Rubber

Synonyms

1-Vinyl-2-pyrrolidinone; 1-Vinyl-2-pyrrolidinone, monomer; 1-Vinyl-2-pyrrolidone; 1-Vinylpyrrolidinone; 1-Vinylpyrrolidone; N-Vinyl-2-pyrrolidinone; N-Vinyl-2-pyrrolidone; N-Vinylpyrrolidinone; N-Vinylpyrrolidone; V-Pyrol; Vinyl-2-pyrrolidone; Vinylbutyrolactam; Vinylpyrrolidinone; Vinylpyrrolidone; [ChemIDplus]

Category

Other Monomers

Description

Clear to light straw colored liquid; [HSDB]

Sources/Uses

Used as a monomer in the production of polyvinyl pyrrolidone; also used in the production of other polymers and organic chemicals; [ACGIH]

Comments

No health effects found in a study of 94 production workers; Animal studies show evidence of liver damage in acute and chronic studies; [ACGIH] An eye and respiratory tract irritant; May cause liver injury; [ICSC] See "N-Methyl-2-pyrrolidone."

Exposure Assessment
Skin Designation (ACGIH)

No

TLV (ACGIH)

0.05 ppm

MAK

0.02 ppm

Vapor Pressure

0.1 mm Hg

Lethal Concentration

LC50 (rat) = 3,200 mg/m3/4h

Explanatory Notes

Flash point = 95 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: