Agent Name

N-Vinyl-2-pyrrolidone

Alternative Name

N-Vinyl-2-pyrrolidinone

CAS Number

88-12-0

Formula

C6-H9-N-O

Major Category

Plastics & Rubber

Synonyms

1-Vinyl-2-pyrrolidinone; 1-Vinyl-2-pyrrolidinone, monomer; 1-Vinyl-2-pyrrolidone; 1-Vinylpyrrolidinone; 1-Vinylpyrrolidone; N-Vinyl-2-pyrrolidinone; N-Vinyl-2-pyrrolidone; N-Vinylpyrrolidinone; N-Vinylpyrrolidone; V-Pyrol; Vinyl-2-pyrrolidone; Vinylbutyrolactam; Vinylpyrrolidinone; Vinylpyrrolidone; [ChemIDplus]

Category

Other Monomers

Description

Clear to light straw colored liquid; [HSDB]

Sources/Uses

Used as a monomer in the production of polyvinyl pyrrolidone; also used in the production of other polymers and organic chemicals; [ACGIH]

Comments

No health effects found in a study of 94 production workers; Animal studies show evidence of liver damage in acute and chronic studies; [ACGIH] An eye and respiratory tract irritant; May cause liver injury; [ICSC] See "N-Methyl-2-pyrrolidone."

Exposure Assessment
Skin Designation (ACGIH)

No

TLV (ACGIH)

0.05 ppm

MAK

0.02 ppm

Vapor Pressure

0.1 mm Hg

Lethal Concentration

LC50 (rat) = 3,200 mg/m3/4h

Explanatory Notes

Flash point = 95 deg C;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: