Agent Name

Dextran sulfate

CAS Number

9042-14-2

Major Category

Biological Agents

Synonyms

Dextran polysulfate; Dextran sulfate 500; Dextran sulfuric acid; Dextran sulfuric acid ester; Dextran sulphate; PF 51; Polydextran sulfate; Dextran, hydrogen sulfate; [ChemIDplus]

Category

Polysaccharides

Description

Solid.

Sources/Uses

"Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications." [ChemIDplus]

Comments

Intraperitoneal LD50 (mouse) = 341 mg/kg; [RTECS] See "Dextran."

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