Agent Name

Benzoyl chloride

Alternative Name

Benzoic acid chloride

CAS Number

98-88-4

Formula

C7-H5-Cl-O

Major Category

Toxic Gases & Vapors

Synonyms

Benzoic acid chloride; Benzaldehyde, alpha-chloro-; Benzenecarbonyl chloride; Benzoic acid, chloride; alpha-Chlorobenzaldehyde; [ChemIDplus] UN1736

Category

Acid Halides

Description

Colorless, fuming liquid with a pungent odor; [HSDB] Colorless to slightly brown liquid; [CHRIS]

Sources/Uses

Used in chemical production; [HSDB]

Comments

Corrosive to skin; [Quick CPC] A lachrymator; High inhalation exposure can cause pulmonary edema; [HSDB] A corrosive substance that can cause pulmonary edema; [ICSC] In lethal concentration studies, rats had labored breathing and histological evidence of emphysema; Hydrolyzes to produce corrosive HCl in biological systems, and this is the mechanism of toxicity; Danger of dermal sensitization; [AIHA] Slowly reacts with water forming hydrochloric acid (reacts more rapidly with steam); Short-term exposure causes second- and third-degree skin burns and severe eye injury; Vapors cause severe eye and throat irritation (and possibly eye and lung injury) and are intolerable even at low concentrations; [CHRIS] Human inhalation of 2 ppm for 1 minute causes other changes in olfaction and lungs, thorax, or respiration; [RTECS] Causes burns; A lachrymator; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; May cause skin sensitization; Harmful by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

Ceiling (ACGIH)

0.5 ppm

WEEL

Ceiling = 5 ppm

Vapor Pressure

0.4 mm Hg

Lethal Concentration

LC50 (rat) = 1,870 mg/m3/2hr

Explanatory Notes

Flash point = 68 deg C;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Probable Carcinogen

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.