Agent Name

tert-Butyl hydroperoxide

CAS Number

75-91-2

Formula

C4-H10-O2

Major Category

Other Classes

Synonyms

1,1-Dimethylethyl hydroperoxide; 1,1-Dimethylethylhydroperoxide; 2-Hydroperoxy-2-methylpropane; Cadox TBH; DE 488; DE-488; Hydroperoxide, 1,1-dimethylethyl; Hydroperoxide, tert-butyl; Hydroperoxyde de butyle tertiaire [French]; Perbutyl H; Slimicide; Slimicide DE-488; T-Butyl hydroperoxide; TBHP-70; Tertiary butyl hydroperoxide; Trigonox A-75 [Czech]; Trigonox A-W70; t-Butylhydroperoxide; terc. Butylhydroperoxid [Czech]; terc.Butylhydroperoxid [Czech]; tert-Butyl hydrogen peroxide; tert-Butylhydroperoxide; [ChemIDplus] UN3109

Category

Peroxides, Organic

Description

Colorless liquid with a pungent odor; [ICSC] Odorless, colorless liquid; [CAMEO]

Sources/Uses

Used as a chemical intermediate, a curing agent for polyesters, and a catalyst for polymerization; also used for bleaching and deodorizing; [HSDB] A polymerization initiator used to produce specialty chemicals in closed systems; [ACGIH]

Comments

TLV Basis: irritation of eyes and respiratory tract; mutagenic effects; reproductive effects; Rats exposed by inhalation 6 hours/day for 5 days had histological evidence of respiratory irritation at 91 mg/m3 but not at 20 mg/m3 (approximately 6 ppm); [ACGIH] Corrosive to skin; [Quick CPC] A corrosive substance that can cause injury to the skin, eyes and respiratory tract; [ICSC] Available as a 70% solution; Causes burns; Inhalation of high concentration can cause chemical pneumonitis; [MSDSonline]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.1 ppm

Vapor Pressure

5.46 mm Hg

Odor Threshold Low

0.05 ppm

Lethal Concentration

LC50 (rat) = 460 ppm/4H

Explanatory Notes

Flash point = 43 deg (may explode on heating); [ACGIH]

Adverse Effects
Toxic Pneumonitis

Yes

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: