Agent Name

Chloroacetic acid

Alternative Name

Monochloroacetic acid

CAS Number

79-11-8

Formula

C2-H3-Cl-O2

Major Category

Other Classes

Synonyms

Monochloroacetic acid; Acetic acid, chloro-; Acide chloracetique [French]; Acide chloracetique [ISO-French]; Acide chloroacetique [French]; Acide monochloracetique [French]; Acidomonocloroacetico [Italian]; Chloracetic acid; Chloroacetic acid; Chloroethanoic acid; Kyselina chloroctova [Czech]; MCA; Monochloorazijnzuur [Dutch]; Monochloracetic acid; Monochloressigsaeure [German]; Monochloroacetic acid; Monochloroethanoic acid; Acetic acid, 2-chloro-; Acetic acid, chloro-; [ChemIDplus] MCA; [AIHA] UN1750; UN1751; UN3250;

Category

Organic Acids

Description

Colorless, white, or light-brown crystals with a vinegar-like odor; [HSDB]

Sources/Uses

Used as a herbicide, preservative, bacteriostat, and chemical intermediate; [HSDB]

Comments

Corrosive to skin; [Quick CPC] Inhalation of aerosol can cause lung edema; May be toxic to the heart, kidneys, and CNS; [ICSC] A severe skin, eye, and respiratory tract irritant; Liquid can burn skin and eyes; [CAMEO] Several accidents have been described; Molten MCA causes severe burns; it is absorbed through the skin; Signs of poisoning include metabolic acidosis, cardiac arrhythmias, disorientation, coma, rhabdomyolysis, renal failure, and cerebral edema; [AIHA]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.5 ppm, inhalable fraction and vapor

WEEL

0.5 ppm

Vapor Pressure

0.06 mm Hg

Odor Threshold Low

0.04 ppm

Odor Threshold High

6.14 ppm

Lethal Concentration

LC50 (rat) = 180 mg/m3

Explanatory Notes

Melting point = 50-63 degrees C; [HSDB] Odor threshold from CHEMINFO; Flash point = 126 deg C;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: