Agent Name

Di-tert-butyl dicarbonate

CAS Number

24424-99-5

Formula

C10-H18-O5

Major Category

Other Classes

Synonyms

Bis(tert-butoxycarbonyl)oxide; BOC-anhydride; Pyrocarbonic acid di-tert-butyl ester; tert-Butoxycarbonyl anhydride; tert-Butyl dicarbonate; Di(tert-butyl) carbonate; Di-tert-butyldicarbonate; Dicarbonic acid, C,C'-bis(1,1-dimethylethyl) ester; Dicarbonic acid, bis(1,1-dimethylethyl) ester; [ChemIDplus] Bis(1,1-dimethylethyl) dicarbonate; Di-tert-butyl oxydiformate; Di-tert-butyl pyrocarbonate; Formic acid, oxydi-, di-tert-butyl ester (7CI,8CI); [RTECS]

Category

Esters, Other

Description

White solid with a mild odor; mp = 22-24 deg C; [Alfa Aesar MSDS]

Sources/Uses

"Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis." [Wikipedia]

Comments

Causes dyspnea and weight loss in inhalation lethal-concentration studies of rats; [RTECS] An irritant that may cause serious eye injury; May cause skin sensitization; Highly toxic by inhalation; [Alfa Aesar MSDS]

Exposure Assessment
Lethal Concentration

LC50 (rat) = 100 mg/m3/4hr

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: