Agent Name

Dithioerythritol

CAS Number

6892-68-8

Formula

C4-H10-O2-S2

Major Category

Biological Agents

Synonyms

(R*,S*)-1,4-Dimercapto-2,3-butanediol; 1,4-Dithioerythritol; DTE; (R*,S*)-1,4-Dimercaptobutane-2,3-diol; 2,3-Butanediol, 1,4-dimercapto-, (2R,3S)-rel-; 2,3-Butanediol, 1,4-dimercapto-, (R*,S*)- (9CI); 2,3-Butanediol, 1,4-dimercapto-, (theta,S)-; Erythritol, 1,4-dithio-; [ChemIDplus] Clelands reagent; Erythro-2,3-Dihydroxy-1,4-butanedithiol; Erythro-1,4-Dimercapto-2,3-butanediol; [Sigma-Aldrich MSDS]

Category

Monosaccharides and Derivatives

Description

White powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used as a reagent to prevent oxidation of sulfhydryl groups and to reduce disulfides to sulfhydryl groups; [ChemIDplus] "Dithioerythritol (DTE) is a sulfur containing sugar derived from the corresponding 4-carbon monosaccharide erythrose." [Wikipedia]

Comments

Causes convulsions in intramuscular lethal-dose studies of mice (LD50 = 309 mg/kg); [RTECS] A skin and strong eye irritant; May cause CNS depression; [Sigma-Aldrich MSDS]

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