Agent Name

2-Ethylhexanoic acid

Alternative Name

Butylethylacetic acid

CAS Number

149-57-5

Formula

C8-H16-O2

Major Category

Other Classes

Synonyms

Butylethylacetic acid; 2-Butylbutanoic acid; 2-Ethylcaproic acid; 2-Ethylhexansaeure; 2-Ethylhexoic acid; 3-Heptanecarboxylic acid; Ethyl hexanoic acid; Ethylhexanoic acid; Ethylhexoic acid; Hexanoic acid, 2-ethyl-; Kyselina 2-ethylkapronova [Czech]; Kyselina heptan-3-karboxylova [Czech]; alpha-Ethylcaproic acid; [ChemIDplus]

Category

Organic Acids

Description

Clear liquid with a mild odor; [HSDB] Colorless to light yellow liquid; [CAMEO]

Sources/Uses

Used as a chemical intermediate for many products; Approximately 400 workers in US manufacturing are potentially exposed; Used in alkyd resins; Used in the mid-1980s as a wood preservative to replace chlorophenols; [ACGIH] Used to make plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors, and alkyd resins; Also used as a co-solvent and defoamer in pesticides, as the active ingredient in the wood preservative Sinesto B (not used in the US), in paint dryers, heat stabilizers for PVC, and as a catalyst for polyurethane foaming, solvent extraction, and dye granulation; [HSDB] Not found in any pesticide products registered in the US; [NPRIS]

Comments

Corrosive to skin; [Quick CPC] High inhalation exposure can cause pulmonary edema; Causes liver changes in feeding studies of rats and mice; [HSDB] The TLV is based on teratogenic effects in animal studies. [ACGIH] May cause second-degree skin burns following short-term contact; Vapors cause severe eye and throat irritation (and possibly eye and lung injury) and are intolerable even at low concentrations; Inhalation may cause chemical pneumonitis and pulmonary edema; [CHRIS] A mild skin irritant; May cause severe eye and mucous membrane irritation; [Alfa Aesar MSDS]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 mg/m3, inhalable fraction and vapor

Vapor Pressure

0.03 mm Hg

Lethal Concentration

LC (rat) > 400 ppm/6hr

Explanatory Notes

Flash point = 118 deg C; [ACGIH]

Adverse Effects
Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: