Agent Name

2-Ethylhexanoic acid

Alternative Name

Butylethylacetic acid

CAS Number

149-57-5

Formula

C8-H16-O2

Major Category

Other Classes

Synonyms

Butylethylacetic acid; 2-Butylbutanoic acid; 2-Ethylcaproic acid; 2-Ethylhexansaeure; 2-Ethylhexoic acid; 3-Heptanecarboxylic acid; Ethyl hexanoic acid; Ethylhexanoic acid; Ethylhexoic acid; Hexanoic acid, 2-ethyl-; Kyselina 2-ethylkapronova [Czech]; Kyselina heptan-3-karboxylova [Czech]; alpha-Ethylcaproic acid; [ChemIDplus]

Category

Organic Acids

Description

Clear liquid with a mild odor; [HSDB] Colorless to light yellow liquid; [CAMEO]

Sources/Uses

Used as a chemical intermediate for many products; Approximately 400 workers in US manufacturing are potentially exposed; Used in alkyd resins; Used in the mid-1980s as a wood preservative to replace chlorophenols; [ACGIH] Used to make plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors, and alkyd resins; Also used as a co-solvent and defoamer in pesticides, as the active ingredient in the wood preservative Sinesto B (not used in the US), in paint dryers, heat stabilizers for PVC, and as a catalyst for polyurethane foaming, solvent extraction, and dye granulation; [HSDB] Not found in any pesticide products registered in the US; [NPRIS]

Comments

Corrosive to skin; [Quick CPC] High inhalation exposure can cause pulmonary edema; Causes liver changes in feeding studies of rats and mice; [HSDB] The TLV is based on teratogenic effects in animal studies. [ACGIH] May cause second-degree skin burns following short-term contact; Vapors cause severe eye and throat irritation (and possibly eye and lung injury) and are intolerable even at low concentrations; Inhalation may cause chemical pneumonitis and pulmonary edema; [CHRIS] A mild skin irritant; May cause severe eye and mucous membrane irritation; [Alfa Aesar MSDS]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 mg/m3, inhalable fraction and vapor

Vapor Pressure

0.03 mm Hg

Lethal Concentration

LC (rat) > 400 ppm/6hr

Explanatory Notes

Flash point = 118 deg C; [ACGIH]

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: