Disease/Syndrome

Nasopharynx cancer

Category

Cancer, Occupational

Acute/Chronic

Chronic

Synonyms

Nasopharyngeal Cancer (NPC); Nasopharyngeal neoplasms; Cancer of nasopharynx

Biomedical References

Search PubMed

Comments

There is suggestive evidence that mustard gas and formaldehyde can cause occupational nasopharyngeal cancer. [Siemiatycki, p. 334] Formaldehyde is a Group 1 carcinogen with sufficient evidence that it caused nasopharyngeal cancer in humans. "There is sufficient evidence in humans for the carcinogenicity of wood dust. Wood dust causes cancer of the nasal cavity and paranasal sinuses and of the nasopharynx." [IARC 2012] In conjunction with earlier studies, a pooled analysis involving close to 29,000 wood workers in Britain and the United States (Demers et al., 1995), and two recent large-scale case-control studies in separate Chinese populations (Armstrong et al., 2000; Hildesheim et al., 2001) have yielded strong evidence that intense exposure to wood dust (as occurs under occupational settings) is associated with a duration-dependent, increased risk of NPC." [Schottenfeld, p. 624]

Latency/Incubation

Years to decades

Diagnostic

Biopsy

ICD-9 Code

147

Reference Link

IARC Monographs: Formaldehyde

Related Information in Haz-Map
Agents

Hazardous agents that cause the occupational disease: