Agent Name

Hydrazine hydrate

CAS Number

7803-57-8

Formula

H4-N2.H2-O

Major Category

Nitrogen Compounds

Synonyms

Hydrazine hydroxide; Hydrazine monohydrate; Hydrazinium hydroxide; Idrazina idrata [Italian]; Hydrazine, hydrate (6CI,7CI); Hydrazine, monohydrate; [ChemIDplus] UN2030

Category

Hydrazines

Description

A colorless fuming liquid with a faint ammonia-like odor; Corresponds to a 64% aqueous solution of hydrazine in water; [CAMEO]

Sources/Uses

Used as a reducing agent and solvent for organic materials; Also used to make "Helman" catalyst (80% hydrazine hydrate that is used in V-2 type rockets) and mixed with methanol for rocket engine propulsion; [Merck Index]

Comments

Corrosive to skin; [Quick CPC] Highly toxic by inhalation, ingestion, or skin absorption; [CAMEO] A very strong reducing agent and violent poison; May cause delayed eye irritation; [Merck Index] Causes methemoglobinemia and liver injury in 28-day oral study of rats at 30 mg/kg/day; [ToxPlanet: JECDB] Causes excitement and muscle contraction or spasticity in oral lethal-dose studies of guinea pigs, mice, rabbits, and rats; [RTECS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; May cause skin sensitization; Toxic by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS] See "Hydrazine."

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
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