Methyl vinyl ketone

3-Buten-2-one

78-94-4

C4-H6-O

Toxic Gases & Vapors

3-Buten-2-one; 1-Buten-3-one; 2-Butenone; 3-Butene-2-one; 3-Butenone-2; Acetone, methylene-; Acetyl ethylene; Butenone; Ketone, methyl vinyl; Methyl ethenyl ketone; Methyl-vinyl-cetone [French]; Methylene acetone; Methylvinyl ketone; Methylvinylketon [German]; Methylvinylketone; Vinyl methyl ketone; delta(sup 3)-2-Butenone; gamma-Oxo-alpha-butylene; Methyl vinyl ketone, stabilized; [ChemIDplus] UN1251

Other Toxic Gases & Vapors

Colorless liquid with a pungent odor; [HSDB] Colorless to pale yellow liquid with a strong irritating odor; [CHRIS]

Used as an intermediate in chemical synthesis, an alkylating agent, and a monomer in resins; it is present in cigarette smoke; [HSDB]

Highly toxic; [Quick CPC] A lachrymator; Can cause liver injury (animal studies); Potential for pulmonary edema after heavy inhalation exposure; [HSDB] Causes lachrymation; May cause skin sensitization; [ICSC] Liquid causes second or third degree burns on short contact; [CHRIS] May polymerize exothermically if heated, exposed to sunlight, or contaminated; [CAMEO] Danger of skin sensitization; [MAK] A severe skin irritant (1% solution); Causes acute pulmonary edema, emphysema, and other liver changes in inhalation lethal-concentration studies of rats; Causes impaired liver function tests in repeated-dose inhalation studies of rats; [RTECS] Methyl vinyl ketone, stabilized (UN1251) has warning of explosive polymerization; [ERG 2016]

Yes

Yes

0.2 ppm

83.9 mm Hg

0.2 ppm

LC50 (rat) = 7 mg/m3/4hr

Yes

See "2018 Notice of Intended Changes." [TLVs and BEIs]

Yes

Yes

Yes

Hepatotoxin, Secondary

Skin Burns

Human Health Effects from Hazardous Substances Data Bank:

• METHYL VINYL KETONE

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Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Pneumonitis, toxic

Activities with risk of exposure:

• Smoking cigarettes