Agent Name

Phosphorus tribromide

CAS Number

7789-60-8

Formula

Br3-P

Major Category

Other Classes

Synonyms

Phosphorous bromide; Phosphorous tribromide; Phosphorus bromide (PBr3); Tribromophosphine; [ChemIDplus] Phosphorus (III) bromide; UN1808

Category

Phosphorus Compounds

Description

Colorless to yellow liquid with a very penetrating odor; [HSDB]

Sources/Uses

Used as a catalyst and in chemical analysis and synthesis; [HSDB]

Comments

Corrosive to skin; [Quick CPC] Inhalation can cause severe irritation of lungs; [CAMEO] Reacts with moisture in the air forming phosphonic acid and hydrogen bromide gas; Causes severe burns; Inhalation may cause chemical pneumonitis and pulmonary edema; [HSDB] Reacts violently with water producing white fumes of hydrogen bromide; Causes burns; Inhalation causes severe irritation of nose, throat, and lungs; [CHRIS] Causes somnolence, muscle weakness, and dyspnea in oral lethal-dose studies of rats; [RTECS]

Exposure Assessment
TIH

Yes

Dangerous When Wet

Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004]

Explanatory Notes

VP = 10 mmHg at 47.8 degrees C; [HSDB] Not TIH in land-based spills, but TiH substance released when spilled in water; [ERG 2016]

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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