Agent Name

Trifluoroacetyl chloride

CAS Number

354-32-5

Formula

C2-Cl-F3-O

Major Category

Toxic Gases & Vapors

Synonyms

Perfluoroacetyl chloride; Acetyl chloride, 2,2,2-trifluoro-; Acetyl chloride, trifluoro-; [ChemIDplus] UN3057

Category

Acid Halides

Description

A colorless gas; [CAMEO] Colorless liquefied gas with a pungent odor; [Halocarbon MSDS]

Comments

Corrosive to skin; [Quick CPC] Evaporating liquid can cause frostbite; A severe skin, eye, and mucous membrane irritant; [CAMEO] Causes dyspnea in inhalation lethal-concentration studies of mice, guinea pigs, and rats; [RTECS] Causes severe burns; Reacts violently with water releasing acidic gas, which in contact with metal, can produce explosive hydrogen gas; Toxic by inhalation--irritating to the respiratory tract; A lachrymator; [MSDSonline]

Exposure Assessment
TIH

Yes

Lethal Concentration

LCLo (rat) = 35.3 ppm/6hr

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: