Agent Name

Methyl (n-amyl) ketone

CAS Number

110-43-0

Formula

C7-H14-O

Major Category

Solvents

Synonyms

2-Heptanone; 2-Heptanone (natural); Amyl methyl ketone; Amyl-methyl-cetone [French]; Butylacetone; Ketone C-7; Ketone, methyl pentyl; Methyl amyl ketone; Methyl n-amyl ketone; Methyl n-pentyl ketone; Methyl pentyl ketone; Methyl-amyl-cetone [French]; Methyl-n-amylketone; Pentyl methyl ketone; n-Amyl methyl ketone; n-Pentyl methyl ketone; [ChemIDplus] UN1110

Category

Ketones (<C12)

Description

Colorless to white liquid with a banana-like, fruity odor; [NIOSH]

Sources/Uses

Used as a solvent for resins and lacquers, a fragrance for cosmetics, and a flavor for foods; [HSDB]

Comments

A potential CNS depressant after inhalation; [CAMEO]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

50 ppm

PEL (OSHA)

100 ppm

IDLH (NIOSH)

800 ppm

Excerpts from Documentation for IDLHs

Other animal data: Exposures to guinea pigs lasting 48 hours were irritating to the mucous membranes at 1,500 ppm, strongly narcotic at 2,000 ppm, and caused narcosis and death at 4,800 ppm [Specht et al. 1940]. Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

3.85 mm Hg

Odor Threshold Low

0.18 ppm

Odor Threshold High

0.19 ppm

Lethal Concentration

LCLo (rat) = 4,000 ppm/4H

Explanatory Notes

Odor threshold from AIHA; Flash point = 39 deg C;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: