Agent Name

Glucose-6-phosphate dehydrogenase

CAS Number

9001-40-5

Formula

Unspecified

Major Category

Biological Agents

Synonyms

Glucosephosphate Dehydrogenase; G6PDH; Dehydrogenase, glucose 6-phosphate; [ChemIDplus] Glucose-6-phosphate Dehydrogenase, from baker's yeast (S. cerevisiae); Zwischenferment; G-6-P-DH; [Sigma-Aldrich MSDS] G6PD;

Category

Enzymes

Description

Powder; [Sigma-Aldrich MSDS]

Sources/Uses

G6PD deficiency is an X-linked red blood cell (RBC) enzyme deficiency with 3 variants in which RBC hemolysis occurs after ingesting of oxidant drugs, febrile illness, or ingestion of fava beans (Class 1 only). [Wallach, p. 805-6]"Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) is a cytosolic enzyme in the pentose phosphate pathway (see image), a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). . . . It is notable in humans when there is a genetic deficiency of G6PD which predisposes to non-immune hemolytic anemia." [Wikipedia]

Comments

May cause irritation; [Sigma-Aldrich MSDS] See "ENZYMES."

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