| Agent Name | Triisobutylaluminum |
|---|---|
| CAS Number | 100-99-2 |
| Formula | C12-H27-Al |
| Major Category | Metals |
| Synonyms | Aluminum, triisobutyl-; Aluminum, tris(2-methylpropyl)-; Tibal; Triisobutyl aluminum; Triisobutylalane; Triisobutylaluminium; Triisobutylaluminum; Tris(2-methylpropyl)aluminum; Tris(isobutyl)alane; Tris(isobutyl)aluminum; [ChemIDplus] TIBA; [CHEMINFO MSDS] UN3051 |
| Category | Metals, Organic Compounds |
| Description | Colorless liquid; [HSDB] |
| Sources/Uses | Used as a chemical intermediate and a polymerization catalyst to produce polybutadiene, polyisoprene, and polypropylene; [HSDB] Organic aluminum compounds are "some of the most important, highest volume, highest value organometallic compounds in production." [Ullmann] |
| Comments | In animal studies, heavy inhalation exposure causes CNS depression and dyspnea. [ChemIDplus] Liquid may cause second or third degree burns after brief skin contact. [CHRIS] Inhalation can induce acute pulmonary edema; [CHEMINFO MSDS] Organoaluminum compounds are corrosive; Harmful if absorbed through the skin or inhaled; The butyl alkyls and below are pyrophoric; Aluminum alkyls are eye irritants; [HSDB] Organic aluminum compounds can cause irritation or burns, depending upon concentration; [Ullmann] TLV withdrawn for aluminum alkyls because of inadequate toxicological data; [ACGIH] Pyrophoric; Reacts violently with water evolving flammable gas; [CAMEO] See "Aluminum." See "ORGANOMETALS." |
| Exposure Assessment | |
| Vapor Pressure | 0.13 mm Hg |
| Lethal Concentration | LCLo (rat) = 8,000 ppm/1hr |
| Explanatory Notes | TLV withdrawn in 2008 with adoption of "Aluminum metal and insoluble compounds"; TLV not recommended for soluble nor for alkyl Al compounds; [ACGIH] The Guide in the Emergency Response Guidebook is for "Aluminum alkyls." |
| Adverse Effects | |
| Toxic Pneumonitis | Yes |
| Neurotoxin | Other CNS Neurotoxin |
| Dermatotoxin | Skin Burns |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Triisobutylaluminum
CAS Number
100-99-2
Formula
C12-H27-Al
Major Category
Metals
Synonyms
Aluminum, triisobutyl-; Aluminum, tris(2-methylpropyl)-; Tibal; Triisobutyl aluminum; Triisobutylalane; Triisobutylaluminium; Triisobutylaluminum; Tris(2-methylpropyl)aluminum; Tris(isobutyl)alane; Tris(isobutyl)aluminum; [ChemIDplus] TIBA; [CHEMINFO MSDS] UN3051
Category
Metals, Organic Compounds
Description
Colorless liquid; [HSDB]
Sources/Uses
Used as a chemical intermediate and a polymerization catalyst to produce polybutadiene, polyisoprene, and polypropylene; [HSDB] Organic aluminum compounds are "some of the most important, highest volume, highest value organometallic compounds in production." [Ullmann]
Comments
In animal studies, heavy inhalation exposure causes CNS depression and dyspnea. [ChemIDplus] Liquid may cause second or third degree burns after brief skin contact. [CHRIS] Inhalation can induce acute pulmonary edema; [CHEMINFO MSDS] Organoaluminum compounds are corrosive; Harmful if absorbed through the skin or inhaled; The butyl alkyls and below are pyrophoric; Aluminum alkyls are eye irritants; [HSDB] Organic aluminum compounds can cause irritation or burns, depending upon concentration; [Ullmann] TLV withdrawn for aluminum alkyls because of inadequate toxicological data; [ACGIH] Pyrophoric; Reacts violently with water evolving flammable gas; [CAMEO] See "Aluminum." See "ORGANOMETALS."
Exposure Assessment
Vapor Pressure
0.13 mm Hg
Lethal Concentration
LCLo (rat) = 8,000 ppm/1hr
Explanatory Notes
TLV withdrawn in 2008 with adoption of "Aluminum metal and insoluble compounds"; TLV not recommended for soluble nor for alkyl Al compounds; [ACGIH] The Guide in the Emergency Response Guidebook is for "Aluminum alkyls."
Adverse Effects
Toxic Pneumonitis
Yes
Neurotoxin
Other CNS Neurotoxin
Dermatotoxin
Skin Burns
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap