Agent Name

Hexamethylene diisocyanate homopolymer

CAS Number

28182-81-2

Formula

(C8-H12-N2-O2)x-

Major Category

Plastics & Rubber

Synonyms

1,6-Diisocyanatohexane homopolymer; Hexamethylene diisocyanate polymer; Hexamethylene diisocyanate trimer; Hexamethylene diisocyanate, homopolymer; Hexamethylene isocyanate polymer; Poly(hexamethylene diisocyanate); Hexane, 1,6-diisocyanato-, homopolymer; Isocyanic acid, hexamethylene ester, polymers; [ChemIDplus] DESMODUR N 3400; 1,6-Hexamethylene Diisocyanate Based Polyisocyanate; [Bayer Material Science MSDS]

Category

Polymers

Description

Clear light yellow liquid; Nearly odorless; [Bayer Material Science MSDS]

Sources/Uses

Used as an industrial coating; [REPROTOX]

Comments

Contains 0.1-0.5% hexamethylene-1,6-diisocyanate (CAS# 822-06-0); Slowly reacts with water evolving carbon dioxide; An irritant that may cause transient corneal injury; May cause skin and respiratory sensitization; Inhalation of high concentrations may cause pulmonary edema; Chronic inhalation overexposure may cause lung injury including fibrosis and decreased function; [Bayer Material Science MSDS] See "Hexamethylene diisocyanate."

Exposure Assessment
Vapor Pressure

1.8E-5 mm Hg

Lethal Concentration

LC50 (rat) = 18,500 mg/m3/1hr

Explanatory Notes

LC50 (rat) = 158 mg/m3/4hr; [Bayer Material Science MSDS]

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Fibrogenic

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: