Agent Name

Propargyl bromide

Alternative Name

3-Bromopropyne

CAS Number

106-96-7

Formula

C3-H3-Br

Major Category

Pesticides

Synonyms

1-Brom-2-propin [Czech]; 1-Bromo-2-propyne; 1-Propyne, 3-bromo-; 2-Propynyl bromide; 3-Bromo-1-propyne; 3-Bromopropyne; Gamma-bromoallylene; Propyne, 3-bromo-; Propynyl bromide; gamma-Bromoallylene; UN2345; [ChemIDplus]

Category

Fumigants

Description

Colorless liquid with a pungent odor; [NJ-HSFS]

Sources/Uses

Used as a fumigant, an alkylating agent, and a chemical intermediate; [HSDB]

Comments

In inhalation studies, all rats die when exposed 1000 ppm for 1 hour or 120 ppm for 7 hours. Minor liver and kidney damage occurs at lethal doses. [HSDB] Can burn the skin; A strong lacrimating agent; Inhalation of high concentrations can cause acute pneumonitis; [CAMEO] Undiluted liquid can produce irreversible corneal damage; At concentrations >1500 ppm, can cause coughing, extreme respiratory distress, and delayed pulmonary edema; [AIHA]

Exposure Assessment
WEEL

0.1 ppm

Vapor Pressure

108 mm Hg

Explanatory Notes

Flash point = 50 deg F; Sensitive to shock; Can form explosive metal acetylides after contact with copper, mercury, and silver; [CAMEO] Odor threshold <2 ppm by volume; [AIHA]

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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