Agent Name

Propargyl bromide

Alternative Name

3-Bromopropyne

CAS Number

106-96-7

Formula

C3-H3-Br

Major Category

Pesticides

Synonyms

1-Brom-2-propin [Czech]; 1-Bromo-2-propyne; 1-Propyne, 3-bromo-; 2-Propynyl bromide; 3-Bromo-1-propyne; 3-Bromopropyne; Gamma-bromoallylene; Propyne, 3-bromo-; Propynyl bromide; gamma-Bromoallylene; UN2345; [ChemIDplus]

Category

Fumigants

Description

Colorless liquid with a pungent odor; [NJ-HSFS]

Sources/Uses

Used as a fumigant, an alkylating agent, and a chemical intermediate; [HSDB]

Comments

In inhalation studies, all rats die when exposed 1000 ppm for 1 hour or 120 ppm for 7 hours. Minor liver and kidney damage occurs at lethal doses. [HSDB] Can burn the skin; A strong lacrimating agent; Inhalation of high concentrations can cause acute pneumonitis; [CAMEO] Undiluted liquid can produce irreversible corneal damage; At concentrations >1500 ppm, can cause coughing, extreme respiratory distress, and delayed pulmonary edema; [AIHA]

Exposure Assessment
WEEL

0.1 ppm

Vapor Pressure

108 mm Hg

Explanatory Notes

Flash point = 50 deg F; Sensitive to shock; Can form explosive metal acetylides after contact with copper, mercury, and silver; [CAMEO] Odor threshold <2 ppm by volume; [AIHA]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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