Agent Name

Furan

CAS Number

110-00-9

Formula

C4-H4-O

Major Category

Other Classes

Synonyms

1,4-Epoxy-1,3-butadiene; Axole; Divinylene oxide; Furfuran; Oxacyclopentadiene; Oxole; Tetrole; UN2389; [ChemIDplus]

Category

Ethers, Other

Description

Colorless liquid with an ethereal odor; darkens on exposure to light and air; [HSDB]

Sources/Uses

Used as a chemical intermediate; [HSDB]

Comments

Inhalation can cause anesthesia; Absorbed through skin; [Merck Index] May cause liver damage; Corrosive to the mouth and GI tract in toxicology studies; [HSDB] Causes narcosis; Contact can irritate or burn skin and eyes; [CHRIS] Furan is a skin irritant. [Quick CPC] A respiratory tract irritant; Inhalation of vapor can cause pulmonary edema; [ICSC] Doses as low as 2 mg/kg can cause severe injury to the liver and kidneys. Causes liver tumors in high-dose animal studies; No data on human use; "Worker exposure by all routes should be minimized to the fullest extent possible." [AIHA]

Exposure Assessment
MAK

0.02 ppm

Vapor Pressure

600 mm Hg

Lethal Concentration

LC50 (rat) = 3,398 ppm/1H

Flammability (NFPA)

4: Burns readily

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: