Agent Name

Homogentisic acid

CAS Number

451-13-8

Formula

C8-H8-O4

Major Category

Other Classes

Synonyms

2,5-Dihydroxy-alpha-toluic acid; 2,5-Dihydroxybenzeneacetic acid; 2,5-Dihydroxyphenylacetic acid; Alcapton; Homogentisate acid; Homogentisinic acid; (2,5-Dihydroxyphenyl)acetic acid; Acetic acid, (2,5-dihydroxyphenyl)-; Benzeneacetic acid, 2,5-dihydroxy-; [ChemIDplus]

Category

Organic Acids

Description

Beige crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

Found in plants and in the urine of alkaptonurics; A product of tyrosine and phenylalanine metabolism; [Merck Index] A naturally-occurring phenolic acid and intermediate in the catabolism of aromatic amino acids (phenylalanine and tyrosine); [Wikipedia]

Comments

Causes changes in urine composition in 5-day intermittent intraperitoneal studies of rats; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]

Exposure Assessment
Vapor Pressure

8.18E-7 mm Hg

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

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