Agent Name

Leucine

CAS Number

61-90-5

Formula

C6-H13-N-O2

Major Category

Biological Agents

Synonyms

2-Amino-4-methylpentanoic acid (L); 2-Amino-4-methylvaleric acid (L); (S)-2-Amino-4-methylpentanoic acid; (S)-2-Amino-4-methylvaleric acid; (S)-Leucine; 2-Amino-4-methylpentanoic acid, (S)-; L-(-)-2-Amino-4-methylpentanoic acid; L-Leucine; L-Norvaline, 4-methyl-; L-alpha-Aminoisocaproic acid; Leu; Leucin [German]; Leucina [INN-Spanish]; Leucina [Latin,Spanish]; Leucinum [INN-Latin]; Pentanoic acid, 2-amino-4-methyl-, (S)-; Valeric acid, 2-amino-4-methyl-, (S)-; Leucine, L-; [ChemIDplus] alpha-Aminoisocaproic acid; [Merck Index]

Category

Amino Acids and Derivatives

Description

White solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]

Sources/Uses

An essential amino acid; [Merck Index] Used as a flavoring agent and nutritional supplement for foods; [FDA] Used in biochemical research; [HSDB]

Comments

Teratogenicity and fetal loss observed in high dose animal studies; A more recent oral study of rats showed no adverse effects at 1,000 mg/kg during gestation; No human data available; [REPROTOX] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; Shown to have tumor promoting activity for bladder carcinomas; [Sigma-Aldrich MSDS]

Exposure Assessment
Vapor Pressure

1.34E-8 mm Hg

Links to Other NLM Databases
Health Studies

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