Agent Name

Menadione

CAS Number

58-27-5

Formula

C11-H8-O2

Major Category

Biological Agents

Synonyms

1,4-Naphthalenedione, 2-methyl-; 1,4-Naphthoquinone, 2-methyl-; 2-Methyl-1,4-naftochinon [Czech]; 2-Methyl-1,4-naphthalenedione; 2-Methyl-1,4-naphthochinon [German]; 2-Methyl-1,4-naphthoquinone; 2-Methylnaphthoquinone; 3-Methyl-1,4-naphthoquinone; Aquakay; Aquinone; Hemodal; Juva-K; K-Thrombyl; K-Vitan; Kaergona; Kanone; Kappaxan; Kappaxan (VAN); Kappaxin; Karcon; Kareon; Kativ-G; Kayklot; Kaykot; Kayquinone; Kipca; Kipca-Oil Soluble; Klottone; Koaxin; Kolklot; Memodol; Menadion; Menadionum; Menaphthon; Menaphthone; Menaquinone; Menaquinone 0; Mitenon; Mitenone; MNQ; Panosine; Prokayvit; Synkay; Thyloquinone; Vitamin K0; Vitamin K2(0); Vitamin K3; [ChemIDplus]

Category

Vitamins and Derivatives

Description

Bright yellow solid with a very mild acrid odor; [Merck Index]

Sources/Uses

Synthetic naphthoquinone derivative with the physiologic properties of vitamin K; Used as a supplement and veterinary antidote to bishydroxycoumarin poisoning (including sweet clover poisoning); [Merck Index] Used as an intermediate in phylloquinone production; [IARC]

Comments

A skin and mucous membrane irritant; [HSDB] May cause hemolytic anemia and cellular damage; [IARC] A skin and strong eye irritant; A possible sensitizer; Harmful by ingestion; Targets the kidney, liver, and blood; [Sigma-Aldrich MSDS] See "1,2-Naphthoquinone."

Exposure Assessment
Vapor Pressure

0.000188 mm Hg

Adverse Effects
IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Other Information

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