Agent Name

Carbonyl sulfide

CAS Number

463-58-1

Formula

C-O-S

Major Category

Toxic Gases & Vapors

Synonyms

Carbon monoxide monosulfide; Carbon oxide sulfide; Carbon oxysulfide; Oxycarbon sulfide; UN2204; [ChemIDplus]

Category

Other Toxic Gases & Vapors

Description

Colorless gas with a rotten egg odor; [CHEMINFO MSDS]

Sources/Uses

Used as a chemical intermediate; Workers may be exposed during petroleum refining, coal destructive distillation, or rayon production; [HSDB] Produced naturally in soil and compost; Other sources are tobacco smoke, burning fossil fuels, gassification, and making petrochemicals; Also used as a grain fumigant and to make drugs, flavors, fragrances, pesticides, and rayon; [ACGIH]

Comments

Liquified gas can cause frostbite; [NJ-HSFS] TLV Basis = CNS impairment; Carbonyl sulfide is less toxic than hydrogen sulfide in animal experiments; A slight methemoglobinemia occurs in animals exposed to > 151 ppm; Adverse effects are due mainly to hydrogen sulfide; [ACGIH] Decomposes to hydrogen sulfide in moist air or lungs; [CHEMINFO MSDS] See "Hydrogen sulfide."

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

TLV (ACGIH)

5 ppm

Vapor Pressure

9410 mm Hg

Lethal Concentration

LC50 (rat) = 1,070 ppm/4H

Flammability (NFPA)

4: Burns readily

Adverse Effects
Toxic Pneumonitis

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Other Poison

Chemical Asphyxiant

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure:

Activities

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