Agent Name

Titanium

CAS Number

7440-32-6

Formula

Ti

Major Category

Metals

Category

Elements, Metallic

Description

Dark gray lustrous metal; [Merck Index]

Sources/Uses

Used in alloys for aerospace, marine, industrial, surgical, and food-handling metal products; Used in x-ray tube targets and ceramic-metal applications; [Hawley]

Comments

Not known to be an essential trace mineral in the diet; Titanium tetrachloride is a strong skin and respiratory tract irritant; Titanium carbide, hydride, nitride, and boride have shown slight fibrogenic activity in studies of experimental animals; Injection of titanium metal into rats has induced fiborsarcomas and lymphosarcomas; A 3-generation study of reproductive toxicity in rats showed some effects after chronic feeding; Titanium dioxide dust has generally been found not fibrogenic and not carcinogenic in epidemiological studies; There is sufficient evidence in animal studies that titanium dioxide is carcinogenic (IARC 2B); [Nordberg, p. 1287-94] See "Titanium dioxide."

Exposure Assessment
Explanatory Notes

"Titanium powder, dry" is spontaneously combustible. [CAMEO] The Guide from the Emergency Response Guidebook is for "titanium powder, dry."

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Processes

Industrial Processes with risk of exposure: