Agent Name

Methyltrichlorosilane

CAS Number

75-79-6

Formula

C-H3-Cl3-Si

Major Category

Toxic Gases & Vapors

Synonyms

Methyl-trichlorsilan [Czech]; Methylsilicochloroform; Methylsilyl trichloride; Monomethyltrichlorosilane; Silane, methyltrichloro-; Silane, trichloromethyl-; Trichlor-methylsilan [Czech]; Trichloromethylsilane; Trichloromethylsilicon; UN1250; [ChemIDplus]

Category

Chlorosilanes

Description

Colorless liquid with a sharp, irritating odor; [CHRIS]

Sources/Uses

Used as a chemical intermediate for silicones; [Hawley]

Comments

Liquid may cause second or third degree burns after brief skin contact. [CHRIS] Reacts violently with water to release hydrogen chloride; Inhalation can cause acute pulmonary edema; [ICSC] Toxicity is due to HCl, which is released when methytrichlorosilane contacts moisture; [AIHA]

Exposure Assessment
Dangerous When Wet

Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004]

WEEL

Ceiling = 1 ppm

Vapor Pressure

167 mm Hg

Lethal Concentration

LC50 (rat) = 450 ppm/4H

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: