| Agent Name | 2,2-Dimethylbutane |
|---|---|
| Alternative Name | Neohexane |
| CAS Number | 75-83-2 |
| Formula | C6-H14 |
| Major Category | Solvents |
| Synonyms | 2,2-Dimethylbutane; Butane, 2,2-dimethyl-; Neohexane; [ChemIDplus] |
| Category | Aliphatics, Saturated (<C12) |
| Description | Colorless liquid with mild gasoline-like odor; [ACGIH] |
| Sources/Uses | Used as solvent (vegetable oils, glues, coatings, and paints); Occur in gasoline, rubber solvent, and petroleum ether; [ACGIH] Used as a high-octane fuel and an intermediate for synthesis of organic chemicals; [Hawley] |
| Comments | After exposure to hexane for 10 minutes, humans experience no effect at 2000 ppm and dizziness or giddiness at 5000 ppm. Like other solvents, hexane isomers are CNS depressants and cardiac sensitizers. Isomers other than n-hexane have the same TLV-TWA. These other isomers include 2,2-dimethylbutane, 2,3-dimethylbutane, 2-methyl pentane, and 3-methyl pentane. [ACGIH] Branched hexanes are less toxic than n-hexane. Cardiac sensitization occurs in dogs inhaling neohexane at 100,000-250,000 ppm. [CHEMINFO] |
| Exposure Assessment | |
| Skin Designation (ACGIH) | Insufficient data |
| TLV (ACGIH) | 500 ppm |
| STEL (ACGIH) | 1000 ppm |
| MAK | 500 ppm |
| Vapor Pressure | 319 mm Hg |
| Adverse Effects | |
| Neurotoxin | CNS Solvent Syndrome |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
Agent Name
2,2-Dimethylbutane
Alternative Name
Neohexane
CAS Number
75-83-2
Formula
C6-H14
Major Category
Solvents
Synonyms
2,2-Dimethylbutane; Butane, 2,2-dimethyl-; Neohexane; [ChemIDplus]
Category
Aliphatics, Saturated (<C12)
Description
Colorless liquid with mild gasoline-like odor; [ACGIH]
Sources/Uses
Used as solvent (vegetable oils, glues, coatings, and paints); Occur in gasoline, rubber solvent, and petroleum ether; [ACGIH] Used as a high-octane fuel and an intermediate for synthesis of organic chemicals; [Hawley]
Comments
After exposure to hexane for 10 minutes, humans experience no effect at 2000 ppm and dizziness or giddiness at 5000 ppm. Like other solvents, hexane isomers are CNS depressants and cardiac sensitizers. Isomers other than n-hexane have the same TLV-TWA. These other isomers include 2,2-dimethylbutane, 2,3-dimethylbutane, 2-methyl pentane, and 3-methyl pentane. [ACGIH] Branched hexanes are less toxic than n-hexane. Cardiac sensitization occurs in dogs inhaling neohexane at 100,000-250,000 ppm. [CHEMINFO]
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
500 ppm
STEL (ACGIH)
1000 ppm
MAK
500 ppm
Vapor Pressure
319 mm Hg
Adverse Effects
Neurotoxin
CNS Solvent Syndrome
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap