Agent Name

Nornicotine

CAS Number

494-97-3; 5746-86-1

Formula

C9-H12-N2

Major Category

Biological Agents

Synonyms

494-97-3: 1'-Demethyl nicotine; 2-(3-Pyridyl)pyrrolidine; 3-(2-Pyrrolidinyl)pyridine; Nornicotin; Pyridine, 3-(2-pyrrolidinyl)-,(S)-; l-Nor-nicotine; Nicotine, 1'-demethyl-, (S)-; Pyridine, 3-(2S)-2-pyrrolidinyl-; [ChemIDplus] (-)-Nornicotine; [RTECS] 5746-86-1: (+-)-1'-Demethylnicotine; (+-)-3-(2-Pyrrolidinyl)pyridine; (+-)-Nornicotine; (R,S)-Nornicotine; Nicotine, 1'-demethyl-, (+-)-; Pyridine, 3-(2-pyrrolidinyl)-, (+-)- (9CI); [ChemIDplus] beta-dl-Nornicotine; [RTECS] DL-Nornicotine; [Alfa Aesar MSDS]

Category

Plant Toxins

Description

Hygroscopic liquid; Develops a mild amine odor; [Merck Index] Colorless or pale yellow liquid; Hygroscopic; [Alfa Aesar MSDS]

Sources/Uses

Found in tobacco and other plants and used as an insecticide; [Merck Index] "Nornicotine is an alkaloid found in various plants including Nicotiana, the tobacco plant. It is chemically similar to nicotine, but does not contain a methyl group. It is a precursor to the carcinogen N-nitrosonornicotine that is produced during the curing and processing of tobacco." [Wikipedia]

Comments

Causes change in cardiac rate and elevated blood pressure in acute subcutaneous studies of rats; [RTECS] A skin and eye irritant; Harmful by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

0.0097 mm Hg

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