Agent Name

Isoprene

CAS Number

78-79-5

Formula

C5-H8

Major Category

Plastics & Rubber

Synonyms

1,3-Butadiene, 2-methyl-; 2-Methyl-1,3-butadiene; 2-Methylbutadiene; 2-Methyldivinyl; 3-Methyl-1,3-butadiene; Isopentadiene; beta-Methylbivinyl; UN1218; [ChemIDplus]

Category

Other Monomers

Description

Colorless liquid with a mild, aromatic odor; [HSDB]

Sources/Uses

Used as a monomer to manufacture polyisoprene and butyl rubber; [HSDB]

Comments

An irritant to the skin, eyes, and mucous membranes; Causes CNS depression at high concentrations; [HSDB] If left on clothes, may cause reddening of skin; [CHRIS] Can affect the CNS, resulting in respiratory depression; [ICSC] Human volunteers complain of slight upper respiratory tract irritation when exposed to 57 ppm; [AIHA]

Exposure Assessment
MAK

3 ppm

WEEL

2 ppm

Vapor Pressure

550 mm Hg

Lethal Concentration

LC50 (rat) = 180,000 mg/m3/4H

Flammability (NFPA)

4: Burns readily

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: