Agent Name

Bicine

CAS Number

150-25-4

Formula

C6-H13-N-O4

Major Category

Other Uses

Synonyms

Bicene; Bis(2-Hydroxyethyl)glycine; DHEG; Diethanol glycine; Diethylolglycine; Dihydroxyethylglycine; Fe-3-Specific; Glycine, N,N-dihydroxyethyl-; N,N-(2-Hydroxyethyl)glycine; N,N-Bis(2-hydroxyethyl)aminoacetic acid; N,N-Bis(2-hydroxyethyl)glycine; N,N-Bis(beta-hydroxyethyl)glycine; N,N-Di(2-hydroxyethyl)glycine; N,N-Dihydroxyethyl glycine; N,N-Dihydroxyethylglycine; Glycine, N,N-bis(2-hydroxyethyl)-; [ChemIDplus] Di(hydroxyethyl)glycine; N,N-Bis(hydroxyethyl)aminoacetic acid; N,N-Di(hydroxyethyl)aminoacetic acid; 2-HxG; [Merck Index]

Category

Biological Buffers

Description

Solid; [Merck Index] White crystalline powder; [Alfa Aesar MSDS]

Sources/Uses

Used as a buffer and chelating agent; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA] "Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 C." [Wikipedia]

Comments

Causes changes in tubules (including acute renal failure and necrosis) in intraperitoneal lethal-dose studies of mice (LD50 = 1,540 mg/kg); [RTECS] May cause irritation; [Alfa Aesar MSDS] See "Glycine."

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