Agent Name

Nerol

CAS Number

106-25-2

Formula

C10-H18-O

Major Category

Biological Agents

Synonyms

(Z)-Geraniol; 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)-; 2-cis-3,7-Dimethyl-2,6-octadien-1-ol; 3,7-Dimethyl-2,6-octadien-1-ol, (Z)-; 3,7-Dimethyl-2,6-octadien-1-ol, cis-; Nerol (natural); Nerol 900; Neryl alcohol; cis-Geraniol; 2,6-Octadien-1-ol, 3,7-dimethyl-, (2Z)-; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Liquid with an odor of sweet rose; [Merck Index] Colorless to pale yellow liquid with a pleasant odor; [CAMEO]

Sources/Uses

Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Present in many essential oils; Used as a base for perfume manufacture; [Merck Index] Also used as a flavoring agent; [CAMEO] The cis-isomer of geraniol; [Merck Index]

Comments

Causes respiratory depression in acute inhalation studies of mice; Causes general anesthesia in oral lethal-dose studies of rats; [RTECS] Mortality, stomach lesions, and cytoplasmic vacuolization (lipidosis) of the liver, kidney, and myocardium in 13-week oral study of mice (LOAEL of 2,000 mg/kg/day); [Reference #1] Safe when used as a flavoring agent in food; [JECFA] A maximization study of 25 volunteers showed no skin sensitization at 4% in petrolatum; [IUCLID] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See "Geraniol."

Reference Link

EPA ChAMP: Terpenoid Primary Alcohols and Related Esters - 2009

Exposure Assessment
Vapor Pressure

0.03 mm Hg

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: