Agent Name

Nisoxetine

CAS Number

57226-61-6; 53179-07-0

Formula

C17-H21-N-O2

Major Category

Other Uses

Synonyms

3-(2-Methoxyphenoxy)-N-methyl-3-phenylpropylamine; 3-(o-Methoxyphenoxy)-N-methyl-3-phenylpropylamine; Compound 89218; DL-N-Methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine; Lilly 135252; N-Methyl-gamma-(2-methylphenoxy)phenylpropanolamine; Benzenepropanamine, gamma-(2-methoxyphenoxy)-N-methyl-; [ChemIDplus]

Category

Biochemical Research

Sources/Uses

"Potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain." [ChemIDplus] Developed by Lilly in the early 1970's for use as an antidepressant; No current clinical applications but is widely used in obesity and energy balance research; [Wikipedia]

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

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