Agent Name

Diketene

CAS Number

674-82-8

Formula

C4-H4-O2

Major Category

Toxic Gases & Vapors

Synonyms

2-Oxetanone, 4-methylene-; 3-Buteno-beta-lactone; 3-Butenoic acid, 3-hydroxy-, beta-lactone; 4-Methylene-2-oxetanone; Ethenone, dimer; Ethenone, dimer (VAN); Ketene, dimer; Vinylaceto-beta-lactone; But-3-en-3-olide; [ChemIDplus]

Category

Other Toxic Gases & Vapors

Description

Colorless liquid with a disagreeable odor; [CAMEO]

Sources/Uses

Used to manufacture paints and pharmaceuticals; [CAMEO]

Comments

A skin and eye irritant; [CAMEO] Inhalation may cause acute pulmonary edema; [ICSC] Diketene, stabilized (UN2521) has warning of explosive polymerization; [ERG 2016] A severe lachrymator--see "Ketene" in CAMEO;

Exposure Assessment
TIH

Yes

IDLH (NIOSH)

8 ppm

Vapor Pressure

10.7 mm Hg

Lethal Concentration

LCLo (rat) = 20,000 ppm/1H

Explosive Polymerization

Yes

Explanatory Notes

Flash point = 90 degrees F; [CAMEO] The Guide from the Emergency Response Guidebook is for "Diketene, inhibitied."

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: