Agent Name

Diketene

CAS Number

674-82-8

Formula

C4-H4-O2

Major Category

Toxic Gases & Vapors

Synonyms

2-Oxetanone, 4-methylene-; 3-Buteno-beta-lactone; 3-Butenoic acid, 3-hydroxy-, beta-lactone; 4-Methylene-2-oxetanone; Ethenone, dimer; Ethenone, dimer (VAN); Ketene, dimer; Vinylaceto-beta-lactone; But-3-en-3-olide; [ChemIDplus]

Category

Other Toxic Gases & Vapors

Description

Colorless liquid with a disagreeable odor; [CAMEO]

Sources/Uses

Used to manufacture paints and pharmaceuticals; [CAMEO]

Comments

A skin and eye irritant; [CAMEO] Inhalation may cause acute pulmonary edema; [ICSC] A severe lachrymator [See "Ketene" in CAMEO.]

Exposure Assessment
TIH

Yes

Vapor Pressure

10.7 mm Hg

Lethal Concentration

LCLo (rat) = 20,000 ppm/1H

Explanatory Notes

Flash point = 90 degrees F; [CAMEO] The Guide from the Emergency Response Guidebook is for "Diketene, inhibitied."

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: