Agent Name

Rhodamine 123

CAS Number

62669-70-9

Formula

C21-H17-N2-O3.Cl

Major Category

Dyes

Synonyms

2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride; 3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride; Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride; RH 123; Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride; [ChemIDplus]

Category

Rhodamine Dyes

Description

Red to brown powder; [Acros Organics MSDS]

Sources/Uses

"A fluorescent probe with low toxicity which is a potent substrate for P-glycoprotein and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of P-glycoprotein in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)" [ChemIDplus]

Comments

May cause irritation; Reports of adverse reproductive effects in experimental animals; [Acros Organics MSDS]

Links to Other NLM Databases
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Other Information

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