Agent Name

DL-Pantolactone

CAS Number

79-50-5

Formula

C6-H10-O3

Major Category

Biological Agents

Synonyms

2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl- (+-)-; [ChemIDplus] (+-)-Dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-one; dl-Lactone; dl-alpha-Hydroxy-beta,beta-dimethyl-gamma-butyrolactone; RS-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone; (RS)-Pantolactone; (+-)-Pantolactone; dl-Pantoyllactone; [OECD SIDS]

Category

Vitamins and Derivatives

Description

White to slightly yellow solid; [OECD SIDS] Colorless hygroscopic crystals; [Sigma-Aldrich MSDS]

Sources/Uses

"Degradation product of pantothenic acid in liver." [ChemIDplus] Used in the syntheses of cosmetics and pharmaceuticals; [OECD SIDS]

Comments

Not irritating to rabbit skin; Not a skin sensitizer in guinea pig maximization test; No reproductive or developmental toxicity observed in sub-chronic oral study of rats at doses up to 1,000 mg/kg/day (mild parental toxicity seen at this dose); [OECD SIDS] May cause irritation; [Sigma-Aldrich MSDS] See "Pantothenic acid."

Exposure Assessment
Vapor Pressure

0.06 mm Hg

Links to Other NLM Databases
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