Agent Name

Demeton-S-methyl

CAS Number

919-86-8

Formula

C6-H15-O3-P-S2

Major Category

Pesticides

Synonyms

2-Ethylthioethyl dimethyl phosphorothioate; Demeton-S-methyl; Demeton-S-metile [Italian]; Demetox; Dimethyl S-(2-eththioethyl)thiophosphate; Duratox; Ethanethiol, 2-(ethylthio)-, S-ester with O,O-dimethyl phosphorothioate; Metaisoseptox; Metaisosystox; Metasystox (I); Metasystox 55; Metasystox J; Methyl demeton thioester; Methyl isosystox; Methyl thionodemeton; Methyl-mercaptofos teolovy (USSR); Methylmercaptofostiol (USSR); Mifatox; O,O-Dimethyl 2-ethylmercaptoethyl thiophosphate, thiolo isomer; O,O-Dimethyl S-(2-(ethylthio)ethyl)phosphorothioate; O,O-Dimethyl S-(2-eththioethyl)phosphorothioate; O,O-Dimethyl S-ethylmercaptoethyl thiophosphate; O,O-Dimethyl-S-(2-aethylthio-aethyl)-monothiophosphat [German]; O,O-Dimethyl-S-(2-ethylthio-ethyl)-monothiofosfaat [Dutch]; O,O-Dimethyl-S-(3-thia-pentyl)-monothiophosphat [German]; O,O-Dimetil-S-(2-etiltio-etil)-monotiofosfato [Italian]; Phosphorothioic acid, O,O-dimethyl S-(2-(ethylthio)ethyl) ester; S-(2-(Ethylthio)ethyl) O,O-dimethyl phosphorothioate; S-(2-(Ethylthio)ethyl) O,O-dimethyl thiophosphate; S-(2-(Ethylthio)ethyl) dimethyl phosphorothiolate; Thiometon oxon; Thiophosphate de O,O-dimethyle et de S-2-ethylthio-ethyle [French]; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Oily, colorless to pale yellow liquid with an unpleasant odor; [ACGIH]

Sources/Uses

Used as an insecticide and acaricide to control aphids, red spider mites, whiteflies, leaf hoppers, and sawflies on vegetables, fruits, and hops; [ACGIH]

Comments

A cholinesterase inhibitor that may cause CNS effects (cardiac disorders, convulsions, cyanosis, and respiratory failure); Can be absorbed through skin; [ICSC] A dermal sensitizer (positive sensitization testing in guinea pigs); [ACGIH]

Restricted

No longer registered for use in the USA; [ACGIH]

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.05 mg/m3, inhalable fraction and vapor

Lethal Concentration

LC50 (rat) = 500 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Skin Sensitizer

Yes

Other Poison

Organophosphate

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: