Agent Name

tert-Amyl methyl ether

Alternative Name

TAME

CAS Number

994-05-8

Formula

C6-H14-O

Major Category

Solvents

Synonyms

TAME; 1,1-Dimethylpropyl methyl ether; 2-Methoxy-2-methylbutane; 2-Methyl-2-methoxybutane; Methyl 1,1-dimethylpropyl ether; Methyl tert-amyl ether; Methyl tert-pentyl ether; TAME (ether); Tertiary amyl methyl ether; tert-Pentyl methyl ether; tertiary-Amyl methyl ether; [ChemIDplus]

Category

Ethers (<C12)

Sources/Uses

Used as a gasoline additive to reduce emissions; [ACGIH]

Comments

Toxicity in animal studies includes CNS depression and increased liver weights; TAME is embryotoxic in high-dose studies of pregnant mice and rats; [ACGIH]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

20 ppm

Vapor Pressure

75 mm Hg

Odor Threshold Low

0.02 ppm

Lethal Concentration

LC50 (rat) = >5,400 mg/m3/4H

Explanatory Notes

Detection odor threshold from ACGIH;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: