Agent Name

Propionitrile

CAS Number

107-12-0

Formula

C3-H5-N

Major Category

Nitrogen Compounds

Synonyms

Cyanoethane; Ethyl cyanide; Propanenitrile; Propionic nitrile; Propiononitrile; [NIOSH] UN2404

Category

Nitriles

Description

Colorless liquid with a pleasant, sweetish, ethereal odor; Note: Forms cyanide in the body; [NIOSH]

Sources/Uses

Used to produce di-n-propylamine; also used as a solvent and dielectric fluid; [HSDB]

Comments

Propionitrile is an occupational hazard by inhalation or skin contact. A 2 minute exposure to saturated vapor killed all rats. A 4 hour exposure to 500 ppm killed 2 of 6 rats. [HSDB] Very toxic by ingestion; The lethal dose is 5 mg/kg or about 7 drops for an adult. Mild to moderate skin and eye irritant; [CAMEO] See "NITRILES."

Exposure Assessment
Vapor Pressure

47.4 mm Hg

Lethal Concentration

LCLo (rat) = 500 ppm/4h

Explanatory Notes

NIOSH REL = 6 ppm; Flash point = 2 deg C;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Other Poison

Chemical Asphyxiant

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: